BRIEF DESCRIPTION OF THE ORGANIZATION
Founded in 1906, Leitat is one of the reference entities at state and European level in technology management. It has a team of more than 500 professionals, experts in applied research, technical services and management of technological and innovation initiatives. Leitat provides social, industrial, economic and sustainable value, offering comprehensive solutions in multiple sectors and areas: development of new materials, eco-sustainable production, occupational health prevention systems, revaluation of waste and use of natural resources, interconnectivity and digitization of industry, green energy and maximization of energy efficiency. Leitat is recognized by the Ministry of Economy, Industry and Competitiveness and is one of the main entities participating in the Horizon2020 and Horizon Europe program of the European Union.
WHAT IS YOUR ROLE IN THE PROJECT?
Leitat will mainly participate in WP2 and WP4.
In WP2 Leitat will shortlist 20 compounds on in vitro studies due to: i) their effects on intestinal barrier protection on Caco-2 cells, ii) immunomodulation on immune cells and iii) stability on plasma and GI fluids.
In WP4 Leitat will perform in vivo studies to characterize the best 4-5 ISI based on: i) their ADME-Tox properties, ii) their preventive and therapeutic effect on DSS-induced colitis model and bacterial translocation and iii) their effects on microbiome and metabolome.